Juvenile Dermatomyositis—Clinical Phenotypes
نویسندگان
چکیده
منابع مشابه
Phenotypes of juvenile idiopathic arthritis
Introduction The term “phenotype” comes from the Greek word “phaino” are is the mix of characteristics and properties of the body, formed in the process of individual development. In medicine phenotype has traditionally been viewed as the result of the interaction of the genotype (genetic characteristics of the organism to the conditions of external environment. Different authors in the allocat...
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Introduction Juvenile idiopathic arthritis (JIA) is a chronic disorder with unknown etiology and characterized by autoimmunity, infiltration of synovium by activated proinflammatory cells, synovial hyperplasia and progressive destruction of cartilage and bone. IL-17A is a proinflammatory cytokine that is expressed in the inflamed synovium. Th17 cells have been identified as main producers of th...
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OBJECTIVE The authors suggest criteria for a range of narrow to broad phenotypes of bipolar disorder in children, differentiated according to the characteristics of the manic or hypomanic episodes, and present methods for validation of the criteria. METHOD Relevant literature describing bipolar disorder in both children and adults was reviewed critically, and the input of experts was sought. ...
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The juvenile idiopathic inflammatory myopathies (JIIM) are systemic autoimmune diseases characterized by skeletal muscle weakness, characteristic rashes, and other systemic features. In follow-up to our study defining the major clinical subgroup phenotypes of JIIM, we compared demographics, clinical features, laboratory measures, and outcomes among myositis-specific autoantibody (MSA) subgroups...
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Autoantibodies targeting intracellular proteins involved in key processes are detected in patients with idiopathic inflammatory myopathies. These myositis-specific autoantibodies have been increasingly demonstrated to correlate with distinct clinical phenotypes within the myositis spectrum. This review highlights the clinical associations of the myositis-specific autoantibodies, with particular...
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ژورنال
عنوان ژورنال: Current Rheumatology Reports
سال: 2019
ISSN: 1523-3774,1534-6307
DOI: 10.1007/s11926-019-0871-4